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Specialized luciferase substrates and vectors enable easy, noninvasive bioluminescence imaging in small animals that improves biological relevance.
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Follow cells of interest in vivo

cells of interest

Mouse with luciferase transgene

stably transfect with luciferase construct

Monitor genetic elements and activation in vivo

pGL4 Vectors

Firefly substrates Renilla substrates

inject cells

inject luciferase substrates

Workflow tools
pGL4 Luciferase Reporter Vectors

VivoGlo™ In Vivo Imaging Substrates NEW! EnduRen™ In Vivo Renilla Luciferase Substrate ViviRen™ In Vivo Renilla Luciferase Substrate

Learn more about in vivo imaging with bioluminescence from these articles:
Identification of apoptotic cells in living reporter mice using modified luciferin Imaging with luciferase in whole animals Selective killing of hypoxia-inducible factor-1-active cells improves survival in a mouse model of invasive and metastatic pancreatic cancer In vivo evaluation of regulatory sequences Bioluminescent imaging of TRAIL-induced apoptosis through detection of caspase activation following cleavage of DEVDaminoluciferin

8901TA

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